R11.16: Cannabis hyperemesis syndrome

New code · FY2026

Billable: use this code on claims.

• New code, effective October 1, 2025 (FY2026).

Code breakdown

Coding notes

Inclusion terms

• Cannabinoid hyperemesis syndrome

Code also

• cannabis abuse (F12.1-)
• cannabis dependence (F12.2-)
• cannabis use, unspecified (F12.92-, F12.93, F12.95-, F12.98-, F12.99)
• manifestations, such as:
• dehydration (E86.0)
• electrolyte imbalance (E87.8)

Excludes1 (from R11)

• cyclical vomiting associated with migraine (G43.A-)
• excessive vomiting in pregnancy (O21.-)
• hematemesis (K92.0)
• neonatal hematemesis (P54.0)
• newborn vomiting (P92.0-)
• psychogenic vomiting (F50.89)
• vomiting associated with bulimia nervosa (F50.2-)
• vomiting following gastrointestinal surgery (K91.0)

Medicare coverage

R11.16 is listed as a covered diagnosis in 5 Medicare billing and coding articles:

• A56389 Billing and Coding: Upper Gastrointestinal Endoscopy and Visualization
• A56421 Billing and Coding: CT of the Abdomen and Pelvis
• A56632 Billing and Coding: Colonoscopy/Sigmoidoscopy/Proctosigmoidoscopy
• A57414 Billing and Coding: Upper Gastrointestinal Endoscopy (Diagnostic and Therapeutic)
• A59186 Billing and Coding: Magnesium

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All FY2026 ICD-10-CM changes

ICD-10-CM codes and descriptions are from the CMS and NCHS code files. Coverage is from the CMS Medicare Coverage Database billing and coding articles.