Home / ICD-10-CM / Other congenital malformations (Q80-Q89)

Q87.88: CTNNB1 syndrome

ICD-10-CM code Q87.88

New code ยท FY2026

Billable: use this code on claims.

  • New code, effective October 1, 2025 (FY2026).

Code breakdown

Q87.88

  1. Q87CategoryOther specified congenital malformation syndromes affecting multiple systems
  2. 8Character 4Other specified congenital malformation syndromes, not elsewhere classified
  3. 8Character 5CTNNB1 syndrome

Coding notes

Use additional code

  • code, if applicable, for associated conditions such as:
  • cerebral palsy (G80.-)
  • congenital heart malformations (Q20.0-Q24.9)
  • developmental disorder of speech and language (F80.-)
  • exudative retinopathy (H35.02-)
  • intellectual disability (F70-F79)
  • microcephaly (Q02)

Excludes1 (from Q87.8)

  • Zellweger syndrome (E71.510)

Use additional code (from Q87)

  • code(s) to identify all associated manifestations

Medicare coverage

Q87.88 is listed as a covered diagnosis in 6 Medicare billing and coding articles:

  • A53060 Billing and Coding: Ophthalmology: Extended Ophthalmoscopy and Fundus Photography
  • A56580 Billing and Coding: Computerized Axial Tomography (CT), Thorax
  • A56612 Billing and Coding: CT of the Head
  • A56625 Billing and Coding: Echocardiography
  • A56775 Billing and Coding: Magnetic Resonance Angiography
  • A57071 Billing and Coding: Ophthalmology: Posterior Segment Imaging (Extended Ophthalmoscopy and Fundus Photography)

Check this code

All FY2026 ICD-10-CM changes

ICD-10-CM codes and descriptions are from the CMS and NCHS code files. Coverage is from the CMS Medicare Coverage Database billing and coding articles.