Home / ICD-10-CM / Chapter 4: Endocrine, nutritional and metabolic diseases (E00-E89) / Metabolic disorders (E70-E88)

E83.821: ENPP1 deficiency causing generalized arterial calcification of infancy

ICD-10-CM code E83.821

New code ยท FY2026

Billable: use this code on claims.

  • New code, effective October 1, 2025 (FY2026).

Code breakdown

E83.821

  1. E83CategoryDisorders of mineral metabolism
  2. 8Character 4Other disorders of mineral metabolism
  3. 2Character 5Disorders of pyrophosphate metabolism
  4. 1Character 6ENPP1 deficiency causing generalized arterial calcification of infancy

Coding notes

Code also

  • , if applicable, associated conditions such as:
  • heart failure (I50.-)
  • other secondary hypertension (I15.8)

Excludes1 (from E83)

  • dietary mineral deficiency (E58-E61)
  • parathyroid disorders (E20-E21)
  • vitamin D deficiency (E55.-)

Check this code

All FY2026 ICD-10-CM changes

ICD-10-CM codes and descriptions are from the CMS and NCHS code files. Coverage is from the CMS Medicare Coverage Database billing and coding articles.